Darwin Global Management, Ltd.

CIK 0001839209 · Q1 2026

13F Equity AUM

$3.8B

-23.7% QoQ

Positions

0 QoQ

AUM Rank

#1,191

Top 10%

Skill Alpha (FF)

+10.3%/yr^ns

No Clear Edge

Rank #286 · Top 4%

vs S&P -11.1%/yr (unadj.)

Quarters Tracked

~5 years

Portfolio Concentration

Top 5: 100.0%Top 10: 100.0%Top 20: 100.0%

IM8N68.3%

BLTE12.1%

ABVX9.3%

RVMD5.4%

ROIV4.8%

DNTH0.0%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare100.0%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 6Median: 7.39%Avg: 16.67%

0–0.5%

1(0.0%)

0.5–1%

0(0.0%)

1–3%

0(0.0%)

3–5%

1(4.8%)

5%+

4(95.2%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 6Unique: 0vs 20 funds

0.1%Low

Fund positions

7,299

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

Most Similar Funds

Top 9 benchmark funds with highest portfolio overlap (Jaccard similarity)

MORGAN STANLEY

0.1%

GEODE CAPITAL MANAGEMENT, LLC

0.2%

0.1%

0.1%

0.2%

0.1%

BANK OF AMERICA CORP /DE/

0.1%

VANGUARD CAPITAL MANAGEMENT LLC

0.1%

VANGUARD PORTFOLIO MANAGEMENT LLC

0.1%

Jaccard similarity per fund: shared CUSIPs / (fund A + fund B − shared). Higher values indicate more similar portfolios.

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Position Changes This Quarter

New3Increased2Decreased1Exited3

New Positions

RVMD5.4%

+2.2M

ROIV4.8%

+6.8M

DNTH0.0%

+17K

Increased

ABVX9.3%

+290K(+9%)

BLTE12.1%

+30K(+1%)

Decreased

IM8N68.3%

-4,128,093(-20%)

Exited

CDTX

-997,196

WVE

-7,298,421

CAPR

-800,000

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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