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Institutional ownership roughly stable: +0.08% change quarter-over-quarter.
Data as of Q1 2026
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Total shares institutions bought (green) vs sold (red) each quarter across all holders.
Inferred from quarter-over-quarter change in each fund's 13F position (new stakes count as buys, exits as sells). Not tick-level trades.
Solve the discounted cash flow backwards, then stress-test the assumptions.
This company doesn't have positive free cash flow, so a reverse DCF can't be run.
Total return (dividends reinvested) vs the market, from quarter-end prices.
Above 0 = ahead of the S&P 500 since the window start; below 0 = behind. Rising means it's pulling ahead.
How far the stock fell below its prior peak. Deeper, longer drawdowns = a rougher ride to the same return.
Quarter-end, dividend-adjusted (total return). Beta & volatility from quarterly returns (annualized). Benchmark is the S&P 500 (SPY total return). Annual returns compound the quarters ending in each calendar year; the first and last years in a window may be partial. Past performance doesn't predict future results.
Top 40 institutional holders — bubble size is position value, color is the move since last quarter. Hover any holder for detail.
Drag any bubble to rearrange · size = dollar value of the position
EOD close · as of 2026-09-17
How a revenue dollar becomes profit — FY2025
Each value shows its share of revenue below it (common-size).
| Line Item | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | FY2020 | FY2019 | FY2018 | FY2017 | FY2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $146.1M 100.0% | $145.2M 100.0% | $146.0M 100.0% | $157.1M 100.0% | $209.8M 100.0% | $108.1M 100.0% | $40.9M 100.0% | $30.3M 100.0% | $1.6M 100.0% | $154K 100.0% |
| Research & Development | $125.6M 86.0% | $143.2M 98.6% | $138.8M 95.0% | $148.7M 94.6% | $160.8M 76.7% | $150.8M 139.5% | $122.3M 299.2% | $161.4M 531.9% | $107.3M 6683.7% | $86.9M 56453.2% |
| Selling, General & Admin | $105.2M 72.0% | $115.4M 79.5% | $131.9M 90.3% | $145.4M 92.6% | $143.8M 68.6% | $126.4M 117.0% | $105.4M 257.8% | $48.8M 161.0% | $24.9M 1549.5% | $23.9M 15550.6% |
| Total Operating Expenses | $236.8M 162.1% | $264.7M 182.2% | $275.6M 188.7% | $299.3M 190.5% | $308.1M 146.8% | $279.9M 259.0% | $230.2M 562.9% | $210.2M 693.0% | $132.1M 8233.2% | $110.9M 72003.9% |
| Operating Income | -$90.7M -62.1% | -$119.4M -82.2% | -$129.5M -88.7% | -$142.2M -90.5% | -$98.3M -46.8% | -$171.8M -159.0% | -$189.3M -462.9% | -$179.9M -593.0% | -$130.5M -8133.2% | -$110.7M -71903.9% |
| Interest Expense | $45.8M 31.4% | $37.4M 25.8% | $23.8M 16.3% | $25.0M 15.9% | $26.0M 12.4% | $27.1M 25.1% | $15.6M 38.3% | $2.5M 8.2% | — | — |
| Interest & Investment Income | $2.8M 1.9% | $7.4M 5.1% | $10.9M 7.5% | $2.4M 1.5% | $582K 0.3% | $2.8M 2.6% | $5.4M 13.3% | $4.0M 13.3% | $1.7M 105.8% | $1.3M 833.8% |
| Other Income (Expense), net | -$105.3M -72.1% | $43.1M 29.7% | -$13.2M -9.1% | -$22.7M -14.5% | -$25.5M -12.2% | -$24.1M -22.3% | -$10.3M -25.1% | $1.5M 5.0% | $1.6M 100.7% | $1.3M 840.3% |
| Pretax Income | -$196.0M -134.2% | -$76.4M -52.6% | -$142.8M -97.8% | -$164.9M -105.0% | -$123.8M -59.0% | -$196.0M -181.3% | -$199.6M -488.0% | -$178.4M -588.0% | -$128.9M -8032.5% | -$109.4M -71063.6% |
| Income Tax Expense | $43K 0.0% | $57K 0.0% | $323K 0.2% | $369K 0.2% | $268K 0.1% | $309K 0.3% | $40K 0.1% | $26K 0.1% | $63K 3.9% | $139K 90.3% |
| Net Income | -$196.0M -134.2% | -$76.4M -52.6% | -$143.1M -98.0% | -$165.3M -105.2% | -$124.1M -59.1% | -$196.3M -181.6% | -$199.6M -488.1% | -$178.4M -588.1% | -$129.0M -8036.4% | -$109.6M -71153.9% |
| Per Share | ||||||||||
| EPS (Basic) | $-17.93 | $-9.41 | $-18.79 | $-2.02 | $-1.65 | $-2.72 | — | — | — | — |
| EPS (Diluted) | $-17.93 | $-14.00 | $-18.79 | $-2.02 | $-1.65 | $-2.72 | — | — | — | — |
| Weighted Avg Shares (Basic) | 11K | 8K | 8K | 82K | 75.2M | 72.0M | — | — | — | — |
| Weighted Avg Shares (Diluted) | 11K | 8K | 8K | 82K | 75.2M | 72.0M | — | — | — | — |
Source: SEC EDGAR XBRL filings (annual, fiscal year). Quarterly flow items are derived from cumulative filings; balance-sheet figures are as-of each period end. Ratios and margins are computed, not reported.
Is the value real, and is the business safe? Academic scores + earnings quality + solvency, from SEC filings.
2/7 of the 9 checks — 2 couldn't be scored (see above), so the score is out of the 7 with data.
Safe > 2.99 · grey 1.81–2.99 · distress < 1.81
Needs granular two-year detail (receivables, PP&E, D&A, SG&A) — not fully reported.
Cash-conversion data unavailable. Lower/negative accruals = higher quality (Sloan).
Interest coverage is thin — monitor.
F-Score (0–9 fundamental momentum), Altman Z (distress risk), and Beneish M (earnings-manipulation screen) are academic models computed from the SEC filings. Screens and context — educational, not recommendations.
What the company returns to shareholders — and whether it's covered by cash.
No dividend to cover. Last year: $0 dividends + $0 buybacks = $0 returned on -$75M FCF.
Yields use the latest fiscal-year dividends/buybacks over current market cap. Dividends and buybacks from the SEC cash-flow statement; payout coverage vs net income and free cash flow. Educational — not a recommendation.
How management deployed cash over 10 years — and what it earned on reinvestment.
A reinvestment story — most cash went back into growth rather than to shareholders.
Reinvestment has been productive — operating income grew well per dollar put in. Current ROIC on all capital: 67%. Rough measure (includes maintenance capex).
Cash uses aggregated from the SEC cash-flow statement over 10 fiscal years. "Return on reinvestment" is a rough proxy — operating-income change ÷ cumulative CapEx + M&A — and includes maintenance capex. Educational — not a recommendation.
How much the company owes, how it's trended, and how comfortably it's serviced.
Cash of $61M covers the $5M due within a year 11.7× over. Scheduled principal only (excludes interest & revolver draws). As of 2021-12-31 (10-K).
Insufficient EBITDA/debt history.
Green ≤ 1.5× · amber ≤ 3× · red > 3× (leverage relative to cash earnings).
Thin coverage — earnings barely cover interest.
Cash vs short-term debt unavailable.
Short-term / long-term split not separately reported.
Debt, cash, interest and equity from the SEC balance sheet & income statement. Effective rate = interest ÷ average debt. Maturity ladder from the SEC long-term-debt repayment schedule. Educational — not a recommendation.
EOD close · as of 2026-09-17
Where each multiple sits in its own 13-yr range · 0th pct blended
Dot = today · shaded = middle 50% · line = median. Lower percentile = cheaper vs its own 13-yr history.
Is the profit real, and how strong is the balance sheet?
FY2025 · every deduction from revenue to net income
DuPont — the three levers
Watch the leverage lever — a chunk of ROE comes from the balance sheet.
What the company owes vs. what it holds
Year-by-year maturities aren't in SEC companyfacts (footnote-only), so this shows the debt/cash structure and net leverage instead.
Latest year: profit growth vs revenue growth
Profit and sales moved in opposite directions this year.
Each line as % of revenue — the trend in color
| % of revenue | FY2018 | FY2019 | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|---|---|
| R&D | 531.9 | 299.2 | 139.5 | 76.7 | 94.6 | 95.0 | 98.6 | 86.0 |
| SG&A | 161.0 | 257.8 | 117.0 | 68.6 | 92.6 | 90.3 | 79.5 | 72.0 |
| Operating Income | -593.0 | -462.9 | -159.0 | -46.8 | -90.5 | -88.7 | -82.2 | -62.1 |
| Income Tax | 0.1 | 0.1 | 0.3 | 0.1 | 0.2 | 0.2 | 0.0 | 0.0 |
| Net Income | -588.1 | -488.1 | -181.6 | -59.1 | -105.2 | -98.0 | -52.6 | -134.2 |
Green = margin-favorable vs the row's own range · red = unfavorable.
The metrics that matter, over time
A 30-second read on KPTI: price, valuation, headline fundamentals, and an auto-generated scorecard from SEC filings. Flags are rule-based signals, not recommendations.
Ranked against 1085 sector peers with collected financials. Valuation from latest close × latest fiscal-year fundamentals; 13F conviction as of 2026-03-31.
Percentile is “goodness” within the peer set (100 = best). For valuation and leverage that means cheaper / less-levered ranks higher.
| Company | Mkt cap ▼ | P/E | EV/EBITDA | P/S | Rev gr | Gross | Net | ROE | ROIC | Net D/EBITDA | 13F |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BCAX | $1.24T | — | — | — | — | — | — | -34.4% | -34.4% | — | 143 |
| LLY | $1.03T | 50.2× | — | 15.9× | 44.7% | 83.0% | 31.7% | 77.8% | 29.9% | — | 4,193 |
| AKTX | $894.1B | — | — | — | — | — | — | -61.1% | -61.1% | — | 1 |
| JNJ | $650.5B | 24.5× | — | 6.9× | 6.0% | 67.9% | 28.5% | 32.9% | 20.7% | — | 4,451 |
| ABBV | $467.1B | 111.9× | 33.4× | 7.6× | 8.6% | 70.2% | 6.9% | -129% | 6.6% | 4.2× | 3,895 |
| MRK | $368.2B | 20.2× | — | 5.7× | 1.3% | 74.8% | 28.1% | 34.7% | 17.9% | — | 3,594 |
| UNH | $339.9B | 28.4× | 19.7× | 0.8× | 11.8% | 88.7% | 2.7% | 12.0% | 6.8% | 3.9× | 2,891 |
| AZN | $257.7B | — | — | — | — | — | — | — | — | — | 1,248 |
| TMO | $248.2B | 37.1× | 31.9× | 5.6× | 3.9% | — | 15.0% | 12.6% | 7.0% | 4.9× | 2,481 |
| AMGN | $204.6B | 26.7× | 17.6× | 5.6× | 10.0% | 67.2% | 21.0% | 89.1% | 12.2% | 3.8× | 3,014 |
| GILD | $187.3B | 22.3× | 20.4× | 6.4× | 2.4% | 78.8% | 28.9% | 37.5% | 17.9% | 2.4× | 2,218 |
| ABT | $178.0B | 27.5× | 19.2× | 4.0× | 5.7% | 56.4% | 14.7% | 12.5% | 10.0% | 1.4× | 2,964 |
| PFE | $157.1B | 20.3× | — | 2.5× | -1.6% | 74.3% | 12.4% | 9.0% | 5.1% | — | 2,838 |
| DHR | $150.2B | 42.1× | 31.0× | 6.1× | 2.9% | 59.1% | 14.7% | 6.9% | 5.1% | 3.4× | 2,083 |
| ISRG | $136.2B | 48.7× | 37.5× | 13.5× | 20.5% | 66.0% | 28.4% | 16.0% | 16.0% | — | 2,190 |
| VRTX | $131.1B | 33.7× | 28.8× | 10.9× | 8.9% | 86.2% | 32.9% | 21.2% | 21.2% | — | 1,609 |
| BMY | $127.8B | 18.2× | — | 2.6× | -0.2% | 71.1% | 14.6% | 38.2% | 11.1% | — | 2,431 |
| MDT | $118.8B | 24.9× | 12.6× | 3.3× | 8.4% | 65.0% | 13.2% | 9.7% | 9.4% | 0.2× | 2,114 |
| CVS | $114.7B | 64.9× | 11.5× | 0.3× | 7.8% | 45.0% | 0.4% | 2.4% | 2.4% | 0.0× | 1,795 |
| SYK | $107.1B | 33.4× | 18.4× | 4.3× | 11.2% | 64.0% | 12.9% | 14.5% | 8.5% | 2.5× | 2,196 |
| MCK | $102.5B | 22.9× | 16.2× | 0.3× | 12.4% | 3.6% | 1.2% | -219% | 109% | 1.0× | 1,946 |
| HCA | $96.4B | 15.1× | — | 1.3× | 7.1% | — | 9.0% | -113% | 16.8% | — | 1,346 |
| ELV | $91.4B | 16.4× | 15.5× | 0.5× | 12.5% | 89.4% | 2.8% | 12.9% | 7.6% | 4.2× | 1,397 |
| REGN | $82.6B | 19.0× | 19.8× | 5.8× | 1.0% | — | 31.4% | 14.4% | 13.6% | 0.5× | 1,336 |
| CI | $72.7B | 12.4× | 5.5× | 0.3× | 11.2% | 21.8% | 2.2% | 14.3% | 14.1% | 0.0× | 1,583 |
| KPTI | $33M | — | — | 0.2× | 0.6% | — | -134% | 66.9% | 66.9% | — | 79 |
Peers = companies sharing KPTI's sector (Healthcare) with collected SEC financials. Multiples use the most recent end-of-day close and latest fiscal-year fundamentals (trailing, not forward). Missing cells mean the peer never reported that line item, has no collected price, or has a non-positive denominator. Not investment advice.