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Data from SEC EDGAR filings: company financials and 13F holdings.

Disclaimer: QW Research is provided for informational and educational purposes only and is not investment advice, a recommendation, or an offer to buy or sell any security. Data is derived from public SEC 13F filings and may be incomplete, delayed, or inaccurate. Do not make investment decisions based on this content. QW Research does not share in any profits and accepts no liability for any losses or decisions made using this information. Past performance does not predict future results.

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PRQR — Fundamentals, Valuation & Ownership | QW Research

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ProQR Therapeutics N.V. (PRQR)

Distributing

Institutional distribution: ownership decreased -2.02% quarter-over-quarter.

Data as of Q1 2026

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No collected fundamentals to build a valuation model.

No collected fundamentals for a quality & risk analysis.

No collected fundamentals for a dividends & returns analysis.

No collected fundamentals for a capital-allocation analysis.

No collected fundamentals for a debt & leverage analysis.

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Institutional Ownership

33.1%

of shares outstanding · 67 funds hold it

Ownership Change

2.02 pts

institutions trimmed their stake last quarter

Crowding

84ᵗʰ pctl

more crowded than 84% of tracked stocks

Institutional Value

$56.3M

total position value across all 13F filers

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Institutional Holders

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Buy / Sell Volume by Quarter

Total shares institutions bought (green) vs sold (red) each quarter across all holders.

Inferred from quarter-over-quarter change in each fund's 13F position (new stakes count as buys, exits as sells). Not tick-level trades.

Crowding AnalysisCrowded

Holders67of 5,944

Avg: 68

Uncrowded84th percentileCrowded

Institutional Activity

Buy/Sell Ratio1.09x

57th percentile

24 buying22 selling

+9

New

-6

Closed

-2,122,092

Net shares

Ownership Concentration

Top 5: 55.7%Top 10: 76.3%

ADAGE CAPITAL PARTNERS GP, L.L.C.17.9%

Privium Fund Management B.V.15.7%

Aberdeen Group9.5%

Affinity Asset Advisors,7.0%

Sio Capital Management,5.6%

Others (62)44.3%

Crowding AnalysisCrowded

Holders67of 5,944

Avg: 68

Uncrowded84th percentileCrowded

Institutional Activity

Buy/Sell Ratio1.09x

57th percentile

24 buying22 selling

+9

New

-6

Closed

-2,122,092

Net shares

Ownership Concentration

Top 5: 55.7%Top 10: 76.3%

ADAGE CAPITAL PARTNERS GP, L.L.C.17.9%

Privium Fund Management B.V.15.7%

Aberdeen Group9.5%

Affinity Asset Advisors,7.0%

Sio Capital Management,5.6%

Others (62)44.3%

Conviction-Weighted Ownership

Median weight: 0.20%Avg weight: 0.40%Max: 1.84%High conviction (>1%): 1

ADAGE CAPITAL PARTNERS GP, L.L.C.

Privium Fund Management B.V.

Affinity Asset Advisors,

Sio Capital Management,

DAFNA Capital Management

Kynam Capital Management,

Ikarian Capital,

PLATINUM INVESTMENT MANAGEMENT

Ownership Map

Top 40 institutional holders — bubble size is position value, color is the move since last quarter. Hover any holder for detail.

Size by

Drag any bubble to rearrange · size = dollar value of the position

Ownership Map

Top 40 institutional holders — bubble size is position value, color is the move since last quarter. Hover any holder for detail.

Size by

Drag any bubble to rearrange · size = dollar value of the position

Institutional Trends (8 Quarters)

Performance vs. S&P 500

Total return (dividends reinvested) vs the market, from quarter-end prices.

$10,000 invested 2021-06

$2,760

PRQR · -72%

$18,666

S&P 500 · +87%

−$15,906

behind the index

Total return (5Y)

-72%

S&P 500

+87%

vs. market

-159%

underperformed

Annualized

-22.7%

mkt 13.3%

Volatility

193%

annualized

Beta

3.50

vs S&P 500

Growth of $10,000

Hover the chart to read any quarter

PRQRS&P 500

Year by year

Annual return vs the market

Hover a year to compare.

PRQR (solid)S&P 500 (outline)Green = positive year, red = negative. Number = PRQR's return.

Beat the market

2 / 6 yrs

33% win rate

Best year

+34%

2024

Worst year

-54%

2022

Worst drawdown

-91%

still -78% below peak

Relative strength

Cumulative lead over the S&P 500

Above 0 = ahead of the S&P 500 since the window start; below 0 = behind. Rising means it's pulling ahead.

Downside

Drawdown from peak · max -91%

How far the stock fell below its prior peak. Deeper, longer drawdowns = a rougher ride to the same return.

Quarter-end, dividend-adjusted (total return). Beta & volatility from quarterly returns (annualized). Benchmark is the S&P 500 (SPY total return). Annual returns compound the quarters ending in each calendar year; the first and last years in a window may be partial. Past performance doesn't predict future results.

We haven't collected financials for PRQR yet, so it can't be scored against its Healthcare peers.